Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

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3,361 – 3,375 of 5,528 results

3,361

Medchemexpress LLC 2-quinolinecarboxaldehyde, 8-hydroxy- | 14510-06-6 | MFCD00168962 | 99.6% | 173.17 g·mol⁻1 | C10H7NO2 | 250 MG

8-Hydroxyquinoline-2-carbaldehyde is an organic biochemical reagent used as a synthetic intermediate, analytical standard, and research reagent in life-science and chemical synthesis applications. It contains a hydroxyl-substituted quinoline aldehyde core and is supplied in small laboratory pack sizes for experimental use.

High purity suitable for analytical and synthetic work (99.6% by HPLC).
Molecular formula C10H7NO2 and molecular weight 173.17 g·mol⁻1.
Light yellow to orange solid appearance.
Available in small lab pack sizes for research use.
Store at -20°C, sealed, away from moisture.
Includes batch certificate of analysis with identity and purity data.

Pricing & Availability

3,362

Medchemexpress LLC [3-Cyano-5-[[[2,4-dimethyl-5-[6-(3-pyridinyl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl]amino]carb | 1448316-08-2 | >98.0% | 558.53 | C26H19F5N6OS | 50 MG

BAY-826 is a small-molecule chemical probe that selectively inhibits the receptor tyrosine kinase TIE-2 (TEK). It shows low-nanomolar biochemical potency and potent cellular activity, and is supplied for research use in solid and DMSO solution formats for preclinical mechanism-of-action and signaling studies.

Selective TIE-2 inhibition (Kd = 1.6 nM).
Potent cellular activity (EC50 = 1.3 nM for TIE-2 autophosphorylation in HUVECs).
Characterized kinase selectivity with limited off-target binding.
Available as solid (5-500 mg) and as 10 mM solution in DMSO.
Suitable for preclinical research applications and mechanistic studies.

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3,363

TARGETMOL CHEMICALS INC SCIADOPITYSIN 10MG

Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Sciadopitysin may prevent the development of diabetic osteopathy it exerts its therapeutic effects via upregulation of mitochondrial biogenesis.Sciadopitysin shows protective effects on antimycin A-induced toxicity in osteoblastic MC3T3-E1 cells it may reduce or prevent osteoblasts degeneration.Sciadopitysin can inhibit the A(beta) aggregation and reduce A(beta)-induced toxicity in the primary cortical neurons. purity: 99%

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3,364

eMolecules 103476-89-7 | Leupeptin Hemisulfate | Target Molecule951.200 | C40H78N12O12S | 0.000 | OS(O)(=O)=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O | 10mg | 335412892

Leupeptin Hemisulfate | Target Molecule | 103476-89-7951.200 | C40H78N12O12S | 0.000 | OS(O)(=O)=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O.CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C=O | 10mg | 335412892

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3,365

TARGETMOL CHEMICALS INC MECAMYLAMINE HYDROCHLORI 25MG

Also available in 5 mg 10 mg 50 mg 100 mg 200 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Mecamylamine hydrochloride (Mevasin) is a nicotinic antagonist used as a ganglionic blocker in hypertension. purity: 99%

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3,366

Medchemexpress LLC 5-Amino-8-hydroxyquinoline | 13207-66-4 | 160.18 | 10 MM * 1 ML

5-Amino-8-hydroxyquinoline (5A8HQ; 5AHQ) is an orally active non-competitive 20S proteasome inhibitor. It can inhibit NF-κB activity and induce cancer cell death, showing low cytotoxicity towards normal hematopoietic cells. This compound is used for the research of various cancers, such as leukemia.

Orally active non-competitive 20S proteasome inhibitor
Inhibits NF-κB activity
Induces cancer cell death
Low cytotoxicity towards normal hematopoietic cells
Suitable for cancer research, including leukemia

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3,367

Medchemexpress LLC MI-773 | 1303607-07-9 | 96.3% | 562.50 | 100 MG

MI-773 is a potent MDM2-p53 protein-protein interaction (PPI) inhibitor. It demonstrates high binding affinity against MDM2 and exhibits antitumor activity. An analog, MI-77301, shows even higher binding affinity and more pronounced antitumor activity in various p53 xenograft models.

Potent MDM2-p53 protein-protein interaction (PPI) inhibitor.
High binding affinity against MDM2 (Kd=8.2 nM).
Exhibits antitumor activity.
Analog shows enhanced binding affinity and antitumor activity.
Effective in various p53 xenograft models including osteosarcoma, human prostate, melanoma, colorectal tumor, and human acute lymphoblastic leukemia.

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3,368

Medchemexpress LLC 7-Methylisatin | 1127-59-9 | 161.16 | 25 G

7-Methylisatin is a derivative of Isatin and functions as a molecular block. This product is provided as a solid with a light yellow to orange appearance.

Derivative of Isatin
Utilized as a molecular block
Solid appearance
Light yellow to orange color

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3,369

Medchemexpress LLC 1-tert-Butyl-3-ethoxybenzene | 133073-81-1 | 95.0% | C12H18O | 250 MG

1-tert-Butyl-3-ethoxybenzene is a drug intermediate used for the synthesis of various active compounds. It is for research use only.

Molecular weight: 178.28
Appearance: Liquid
Color: Light yellow to light brown

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3,370

Medchemexpress LLC (S,R,S)-AHPC-amido-C7-acid | 2172819-76-8 | 98.7% | 600.77 | 100 MG

(S,R,S)-AHPC-amido-C7-acid incorporates a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker, making it suitable for designing PROTACs. It is for research use only.

Incorporates a VHL ligand for E3 ubiquitin ligase
Includes a PROTAC linker
Suitable for designing PROTACs
Purity of 98.71%
Molecular weight of 600.77
Appears as a solid
Color is white to off-white
Relevant to cancer research and targeted therapy

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3,371

Medchemexpress LLC LM11A-31 (dihydrochloride) | 1243259-19-9 | 99.9% | 316.27 | 25 MG

LM11A-31 dihydrochloride is a non-peptide p75NTR (neurotrophin receptor p75) modulator and an orally active, potent proNGF (nerve growth factor) antagonist. It is an amino acid derivative that readily crosses the blood-brain barrier and inhibits p75-mediated cell death. This compound has been shown to reverse cholinergic neurite dystrophy in mouse models of Alzheimer's disease during mid- to late-stage disease progression. It is intended for research use only and is not sold to patients.

Non-peptide p75NTR modulator
Orally active and potent proNGF antagonist
Amino acid derivative with high blood-brain barrier permeability
Blocks p75-mediated cell death
Reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models
Mitigates proNGF accumulation and preserves BRB integrity in animal models

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3,372

eMolecules 1227608-04-9 | 7-HYDROXYQUINOLINE-6-CARBOXYLIC ACID | AstaTech | MFCD16659699 | 189.170 | C10H7NO3 | 95.000 | OC(=O)c1cc2cccnc2cc1O | 0.1g | 798867649

7-HYDROXYQUINOLINE-6-CARBOXYLIC ACID | AstaTech | 1227608-04-9 | MFCD16659699 | 189.170 | C10H7NO3 | 95.000 | OC(=O)c1cc2cccnc2cc1O | 0.1g | 798867649

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3,373

Medchemexpress LLC AL-611 | 2481279-61-0 | 99.9% | C25H33F2N6O8P | 1 ML

AL-611 is an HCV NS5B polymerase inhibitor with an EC50 of 5 nM, intended for research use only.

Molecular weight of 614.54.
Purity of 99.93%.
Appears as a solid, white to off-white.
Soluble in DMSO (125 mg/mL).
Store powder at -20°C for up to 3 years.
Store in solvent at -80°C for 6 months, or -20°C for 1 month.
Exhibits CC50 > 100 μM and EC50 0.005 μM in Huh-7 cells.
Involved in a Phase 1 clinical trial for Hepatitis C (NCT03253471).

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3,374

Medchemexpress LLC (S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-carbonyl)isoxazol-5(2H)-one | 654059-21-9 | 99.8% | 266.34 g/mol | C14H22N2O3 | 100 MG

BAY 59-9435 (HSL-IN-2) is a potent, selective small-molecule inhibitor of hormone-sensitive lipase (HSL) with an IC50 of 0.023 μM. It exhibits cellular activity (28 nM in 3T3-L1 cells for inhibition of forskolin-stimulated lipolysis) and is supplied as a high-purity solid for research use, with recommended storage conditions to maintain stability.

Potent and selective HSL inhibition (IC50 0.023 μM).
Demonstrated cellular activity in adipocyte assays (28 nM).
High purity suitable for biochemical and cellular studies.
Stable as powder under recommended storage conditions.
Soluble in DMSO for assay preparation.

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3,375

TARGETMOL CHEMICALS INC MURAGLITAZAR 5MG

Also available in 1 mg 10 mg 25 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Muraglitazar (BMS-298585) is a PPAR (alpha)/(gamma) dual agonist for the treatment of type 2 diabetes and associated dyslipidemia. Muraglitazar shows potent activity in vitro at human PPAR(alpha) and PPAR(gamma) with EC50 of 320 nM and 110 nM respectively. purity: 99%

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Quinolines and derivatives

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Medchemexpress LLC 2-quinolinecarboxaldehyde, 8-hydroxy- | 14510-06-6 | MFCD00168962 | 99.6% | 173.17 g·mol⁻1 | C10H7NO2 | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC [3-Cyano-5-[[[2,4-dimethyl-5-[6-(3-pyridinyl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl]amino]carb | 1448316-08-2 | >98.0% | 558.53 | C26H19F5N6OS | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 5-Amino-8-hydroxyquinoline | 13207-66-4 | 160.18 | 10 MM * 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC MI-773 | 1303607-07-9 | 96.3% | 562.50 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 7-Methylisatin | 1127-59-9 | 161.16 | 25 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1-tert-Butyl-3-ethoxybenzene | 133073-81-1 | 95.0% | C12H18O | 250 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (S,R,S)-AHPC-amido-C7-acid | 2172819-76-8 | 98.7% | 600.77 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC LM11A-31 (dihydrochloride) | 1243259-19-9 | 99.9% | 316.27 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AL-611 | 2481279-61-0 | 99.9% | C25H33F2N6O8P | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-carbonyl)isoxazol-5(2H)-one | 654059-21-9 | 99.8% | 266.34 g/mol | C14H22N2O3 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More